Evaluation of cardiovascular complexities and quality of life


Evaluation of cardiovascular complexities and quality of life

Thyrotoxic heart disease has been classified as the development of various cardiovascular complexities which results because the excess of thyroid hormones affect peripheral vasculature and cardiac myocytes, directly. It could manifest as thyrotoxic cardiomyopathy, ventricular extrasystole, congestive cardiac failure, elevated resting heart rate, atrial fibrillation, arterial high blood pressure (bp), and cardiac hypertrophy. The common cause behind thyrotoxic heart disease is toxic diffuse goiter (TDG), which is associated with hyperthyroidism constituting up to 5% of all endocrine disorders in several countries. Besides, the reason behind the development of psychiatric disorders is the deregulation of thyroid hormones and its influence on neurotransmitters through hyperthyroidism.

Quality of life related to health (QLrH) includes anxiety and depression as prime dimensions along with other dimensions as pain, mobility, discomfort, self-care etc. A number of clinical studies have suggested that hyperthyroidism may lead to anxiety and depression. Concurrently, anxiety and depression may lead to thyroid abnormalities as well as it may lead to various cardiovascular-based risks or even to cardiovascular-based deaths [16] and thus it can be said that depression and cardiovascular-related results are interrelated and this has been established in recent past. Even then, studies in which depression has been assessed by means of interview-validated questionnaires have not been explored much and thus the precise relationship between hyperthyroidism and depression remains unclear. QLrH diminish due to thyrotoxic heart disease along with TDG. Anti-thyroid drugs and β-adrenergic receptor antagonists are the preferential action to deal with TDG in Europe and Southeast Asia because they eliminated hyperthyroidism and normalized the cardiovascular dimensions along with as well as QLrH. Several authors have reported the effect of QLrH in different patients with hyperthyroidism or cardiovascular complexities but up to a limited extent and so far the features of TDG in Chinese patients are less known. Thus our study is the first study of its own kind to reveal the association of thyrotoxic heart disease secondary to TDG with specific focus on quality of life related to health in Chinese patients.

For more kindly go through: Biomedical Research

Biomedical Research accepts direct submissions from authors: Attach your word file with e-mail and send it to biomedres@peerjournal.org

Media Contact:

Joel James
Managing Editor
Biomedical Research